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Six New Isolates of Human Immunodeficiency Virus Type 2 (HIV-2) and the Molecular Characterization of One (HIV-2_CAM2)

¹ Department of Haematological Medicine, University of Cambridge Clinical School, Hills Road, Cambridge CB2 2QL, U.K.
² Hopital de Egas Moniz
and³ Instituto Nacional de Saude Dr Ricardo Jorge, Lisbon, Portugal

We report the isolation of human immunodeficiency virus type 2 (HIV-2) from each of six West Africans with AIDS-related complex or AIDS. One isolate (HIV-2_CAM2) was molecularly cloned and shown by restriction mapping to differ in seven out of 22 sites from the prototype HIV-2_ROD. Nevertheless, by a number of serological criteria these isolates are all clearly HIV-2.

Keywords: HIV-2, cloning, isolates

Received 25 August 1988; accepted 26 October 1988.