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Poxvirus Genetic Recombination during Natural Virus Transmission

AFRC Institute for Animal Health, Pirbright Laboratory, Ash Road, Pribright, Woking, Surrey GU24 0NF, U.K.

We have compared detailed physical maps of the genomes of four capripoxvirus isolates, representing four capripoxvirus genome types. The comparisons strongly suggest that the progenitor of one of these isolates arose by genetic recombination between members of two of the other three types.

Keywords: poxvirus, recombination, evolution

Received 8 July 1988; accepted 13 October 1988.

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