HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Nolan, K. F. Articles by Bishop, D. H. L. Search for Related Content PubMed PubMed Citation Articles by Nolan, K. F. Articles by Bishop, D. H. L. Agricola Articles by Nolan, K. F. Articles by Bishop, D. H. L.

The Design and Use of Specific Genetic Probes to Identify Closely Related Bunyaviruses and to Determine the Genotype of Their Recombinants

NERC Institute of Virology, Mansfield Road, Oxford OX1 3SR, U.K.

Viruses that are very closely related to each other at the genetic and gene product level can prove difficult to distinguish, although they may differ in phenotype (for example in their viruslence or vector preferences). A chimeric genetic probe has been developed and tested to distinguish the S RNAs of two closely related bunyaviruses, snowshoe hare and La Crosse viruses. The technique is applicable to other RNA species of these two bunyaviruses.

Keywords: bunyaviruses, LAC, SSH, S RNAs

Received 13 March 1989; accepted 14 April 1989.