HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Fahey, K. J. Articles by York, J. J. Search for Related Content PubMed PubMed Citation Articles by Fahey, K. J. Articles by York, J. J. Agricola Articles by Fahey, K. J. Articles by York, J. J.

The role of mucosal antibody in immunity to infectious laryngotracheitis virus in chickens

CSIRO Division of Animal Health, Animal Health Research Laboratory, Private Bag No. 1, P.O., Parkville, Victoria 3052, Australia

The role of mucosal antibody in recovery from a primary infection and resistance to reinfection with infectious laryngotracheitis (ILT) herpesvirus was studied in bursectomized chickens, which were unable to synthesize specific antibodies. Viral antigen in the infected trachea was assessed by indirect immunofluorescence on tissue sections and by ELISA. The ability of bursectomized chickens to resolve primary infections as effectively as intact chickens and of vaccinated-bursectomized chickens to prevent the replication of challenge virus without the participation of mucosal antibody, is evidence for the importance of local cell-mediated rather than humoral immune mechanisms in the outcome of infection with ILT virus.

Received 27 April 1990; accepted 3 July 1990.

This article has been cited by other articles:

				J. M. Devlin, G. F. Browning, C. A. Hartley, N. C. Kirkpatrick, A. Mahmoudian, A. H. Noormohammadi, and J. R. Gilkerson Glycoprotein G is a virulence factor in infectious laryngotracheitis virus. J. Gen. Virol., October 1, 2006; 87(Pt 10): 2839 - 2847. [Abstract] [Full Text] [PDF]

				W. Fuchs, D. Wiesner, J. Veits, J. P. Teifke, and T. C. Mettenleiter In Vitro and In Vivo Relevance of Infectious Laryngotracheitis Virus gJ Proteins That Are Expressed from Spliced and Nonspliced mRNAs J. Virol., January 15, 2005; 79(2): 705 - 716. [Abstract] [Full Text] [PDF]