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Molecular analysis of the haemagglutinin gene of an avian H1N1 influenza virus

¹ Virus Research Unit, The Medical Research Council of New Zealand, University of Otago, P.O. Box 56, Dunedin, New Zealand
and² Department of Virology and Molecular Biology, St Jude Children's Research Hospital, 332 N. Lauderdale, P.O. Box 318, Memphis, Tennessee 38101, U.S.A.

This study presents the first nucleotide sequence and deduced primary amino acid sequence of a subtype H1 haemagglutinin from the avian influenza virus A/duck/Alberta/35/76 (H1N1). The molecule is structurally, antigenically and molecularly similar to H1 haemagglutinins of human viruses but sequence homology differences indicate that there has not been a recent transfer of haemagglutinin genetic information between them.

Received 21 February 1990; accepted 5 June 1990.