J Gen Virol Try Microbiology Online
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Gen Virol 71 (1990), 2475-2478; DOI 10.1099/0022-1317-71-10-2475
© 1990 Society for General Microbiology
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Ogura, H.
Right arrow Articles by Nakamura, S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Ogura, H.
Right arrow Articles by Nakamura, S.
Agricola
Right arrow Articles by Ogura, H.
Right arrow Articles by Nakamura, S.

Temperature elevation enhances cell surface expression of measles virus fusion protein in infected cells

Hisashi Ogura1, Hiroshi Sato2, Shigeru Kamiya1 and Shinichi Nakamura1

1 Department of Bacteriology, School of Medicine
and2 Department of Virology, Cancer Research Institute, Kanazawa University, Kanazawa 920, Japan

Cell fusion proceeded gradually in measles virus-infected cells incubated at 35 °C. Shift-up of incubation temperature to 39 °C induced rapidly increased cell fusion in spite of the cessation of de novo synthesis of the fusion (F) protein. Pulse-chase experiments showed that there was little difference in the acquisition of immunoreactivity by haemagglutinin (H) and F proteins between the two temperatures. H protein was detected on the cell surface 60 min after the chase at either temperature. However, appearance of F protein on the cell surface took less than 3 h at 39 °C whereas it took 5 h at 35 °C. These data indicate that temperature elevation induces more efficient expression of F protein on the cell surface accompanied by marked syncytium formation in measles virus-infected cells.

Received 31 January 1990; accepted 11 June 1990.


This article has been cited by other articles:


Home page
 J. Virol.Home page
C. L. Parks, R. A. Lerch, P. Walpita, M. S. Sidhu, and S. A. Udem
Enhanced Measles Virus cDNA Rescue and Gene Expression after Heat Shock
J. Virol., May 1, 1999; 73(5): 3560 - 3566.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
INT J SYST EVOL MICROBIOL MICROBIOLOGY J GEN VIROL
J MED MICROBIOL ALL SGM JOURNALS
Copyright © 1990 by the Society for General Microbiology.