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J Gen Virol 72 (1991), 2533-2535; DOI 10.1099/0022-1317-72-10-2533
© 1991 Society for General Microbiology

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Enzootic nasal tumour of goats: demonstration of a type D-realated retrovirus in nasal fluids and tumours

M. De las Heras1, J. M. Sharp2, J. A. Garcia de Jalon1 and P. Dewar2

1 Histologia y Anatomia Patologia, Facultad de Veterinaria, Universidad de Zaragoza, Spain
and2 Moredun Research Institute, 408 Gilmerton Road, Edinburgh EH17 7JH, U.K.

Nasal exudate and tumour tissue from goats with enzootic nasal tumours were shown to contain a reverse transcriptase activity associated with a particle of buoyant density typical of retroviruses. The same particle contained a 25000 Mr protein that cross-reacted with the p27 of Mason-Pfizer monkey virus (MPMV) and with p25 of sheep pulmonary adenomatosis retrovirus. It also contained a low Mr protein related to p10–12 of MPMV.

Received 11 March 1991; accepted 2 July 1991.


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