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1 Unité d'Immunologie Virale, Department des Rétrovirus
and2 Unité de Biotechnologie Cellulaire, Institut Pasteur, 28, rue du Dr Roux, Paris Cédex 15, France
Human cytomegalovirus (HCMV) induction of growth factors in fibroblasts was investigated after establishing serum-free culture conditions conducive to viral replication. HCMV infection induced a type II heparin-binding growth factor which stimulated human endothelial cell proliferation.
Present address: Sanofi Recherche, Centre Choay, 94258 Gentilly Cédex 30, France.
Received 22 April 1991;
accepted 8 July 1991.
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