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J Gen Virol 72 (1991), 1045-1050; DOI 10.1099/0022-1317-72-5-1045
© 1991 Society for General Microbiology

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Identification of the porcine paramyxovirus LPMV matrix protein gene: comparative sequence analysis with other paramyxoviruses

Mikael Berg, Anita Sundqvist, Jorge Moreno-López and Tommy Linné

Department of Veterinary Microbiology (Molecular Virology), Biomedical Center, Swedish University of Agricultural Sciences, Uppsala S-751 23, Sweden

The complete nucleotide sequence of the gene encoding the matrix protein (M) of the porcine paramyxovirus LPMV has been determined. The gene is 1376 nucleotides long including 5' and 3' non-coding sequences with a protein-coding sequence of 1107 nucleotides. The deduced protein, containing 369 amino acids with a calculated Mr of 41657, is hydrophobic overall with a net positive charge of +17.5. Comparative sequence analysis revealed high amino acid homology to other paramyxovirus M proteins, with the highest degree of identity (46%) with the human mumps virus. This is strong evidence that the porcine paramyxovirus LPMV is a genuine member of the paramyxovirus genus.

Received 15 November 1990; accepted 17 January 1991.





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Copyright © 1991 by the Society for General Microbiology.