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Temporal control of bovine herpesvirus type 4 glycoprotein synthesis

Department of Virology-Immunology, Faculty of Veterinary Medicine, University of Liège, Institut de Chimie (B6), 4000 Liège, Belgium

The glycoprotein gp6/gp10/gp17, gp11/VP24 and gp8 are major bovine herpesvirus type 4 antigens. The temporal expression of these glycoproteins was studied and it was shown that gp6/gp10/gp17 appeared as early as 6 h post-inoculation (p.i.), and gp11/VP24 and gp8 were detected 8 h p.i. Moreover, a precursor of two components of gp6/gp10/gp17 glycoprotein [p(gp10/gp17)] was a beta-gamma protein, whereas the gp11/VP24 and gp8 glycoproteins were gamma proteins.

Received 17 December 1990; accepted 27 February 1991.

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