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The major glycoprotein of Sendai virus is dispensable for efficient virus particle budding

Department of Microbiology, University of Geneva, Medical School, C.M.U., 9 Avenue de Champel, CH-1211 Geneva 4, Switzerland

A temperature-sensitive mutant of Sendai virus, ts271, when grown at restrictive temperature is known to produce virions lacking integral haemagglutinin—neuraminidase (HN). In this study, it is shown that the transmembrane-cytoplasmic tail of HN is not detected either. This apparent complete lack of HN does not affect budding efficiency.

Received 7 January 1991; accepted 13 March 1991.

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