J Gen Virol
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J Gen Virol 72 (1991), 2275-2278; DOI 10.1099/0022-1317-72-9-2275
© 1991 Society for General Microbiology

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The structural polypeptide VP3 of infectious bursal disease virus carries group- and serotype-specific epitopes

Volker Öppling{dagger}, Hermann Müller and Hermann Becht

Institut für Virologie, Justus-Liebig-Universität Giessen, Frankfurter Strasse 107, D-6300 Giessen, Germany

Two independent non-overlapping epitopes could be demonstrated on the structural protein VP3 of infectious bursal disease virus by non-neutralizing monoclonal antibodies produced against serotypes I and II. Both serotypes have one epitope in common, whereas the second epitope is distinct for serotype I and serotype II.

{dagger} Present address: Paul-Ehrlich-Institut, Paul-Ehrlich-Strasse 51-59, D-6070 Langen, Germany.

Received 20 February 1991; accepted 3 May 1991.


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