| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
1 Department of Medicine, School of Medicine,
2 Department of Epidemiology, School of Public Health, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7030
and3 Department of Microbiology, Parasitology and Pathology, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina 27606, U.S.A.
Antisera to a peptide representing the extreme carboxy terminus of the hepatitis delta virus antigen (HDAg) open reading frame (residues 197 to 211) recognized only the large (p27
) and not the small (p24) form of HDAg in immunoblots of infected liver extracts, thereby providing direct proof that p27 and p24 differ in their carboxyl-terminal sequence and that p27 results from mutation within the stop codon terminating translation of p24. Reactions with other peptide antisera demonstrated that multiple smaller virus-specified proteins were carboxy-terminally truncated forms of HDAg, and immunoprecipitation studies suggested that different forms of HDAg were present as heterologous complexes within the liver extract.
Received 15 July 1991;
accepted 17 September 1991.
This article has been cited by other articles:
|
|
 |
|
  S. D. Linnstaedt, W. K. Kasprzak, B. A. Shapiro, and J. L. Casey The role of a metastable RNA secondary structure in hepatitis delta virus genotype III RNA editing RNA, August 1, 2006; 12(8): 1521 - 1533. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Q. Cheng, G. C. Jayan, and J. L. Casey Differential Inhibition of RNA Editing in Hepatitis Delta Virus Genotype III by the Short and Long Forms of Hepatitis Delta Antigen J. Virol., July 15, 2003; 77(14): 7786 - 7795. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. B. Macnaughton and M. M. C. Lai Large Hepatitis Delta Antigen Is Not a Suppressor of Hepatitis Delta Virus RNA Synthesis once RNA Replication Is Established J. Virol., August 28, 2002; 76(19): 9910 - 9919. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. L. Casey RNA Editing in Hepatitis Delta Virus Genotype III Requires a Branched Double-Hairpin RNA Structure J. Virol., June 27, 2002; 76(15): 7385 - 7397. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. C. Jayan and J. L. Casey Increased RNA Editing and Inhibition of Hepatitis Delta Virus Replication by High-Level Expression of ADAR1 and ADAR2 J. Virol., March 19, 2002; 76(8): 3819 - 3827. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Nakano, C. N. Shapiro, S. C. Hadler, J. L. Casey, M. Mizokami, E. Orito, and B. H. Robertson Characterization of hepatitis D virus genotype III among Yucpa Indians in Venezuela J. Gen. Virol., September 1, 2001; 82(9): 2183 - 2189. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Lin, S. Hsu, J. Wu, I. Sheen, B. Yan, and W. Syu Localization of isoprenylated antigen of hepatitis delta virus by anti- farnesyl antibodies J. Gen. Virol., January 1, 1999; 80(1): 91 - 96. [Abstract]
|
|
|
|
|
|
K. Dingle, V. Bichko, H. Zuccola, J. Hogle, and J. Taylor Initiation of Hepatitis Delta Virus Genome Replication J. Virol., June 1, 1998; 72(6): 4783 - 4788. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. C. Otto and P. J. Casey The Hepatitis Delta Virus Large Antigen Is Farnesylated Both in Vitro and in Animal Cells J. Biol. Chem., March 1, 1996; 271(9): 4569 - 4572. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| INT J SYST EVOL MICROBIOL | MICROBIOLOGY | J GEN VIROL |
| J MED MICROBIOL | ALL SGM JOURNALS | |
