J Gen Virol Tips for Better Browsing
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
 QUICK SEARCH:   [advanced]


     


J Gen Virol 74 (1993), 2269-2273; DOI 10.1099/0022-1317-74-10-2269
© 1993 Society for General Microbiology

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Person, S.
Right arrow Articles by Hempel, J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Person, S.
Right arrow Articles by Hempel, J.
Agricola
Right arrow Articles by Person, S.
Right arrow Articles by Hempel, J.

Herpes simplex virus type 1 capsid protein, VP21, originates within the UL26 open reading frame

Stanley Person, Sylvie Laquerre, Prashant Desai and John Hempel

Department of Molecular Genetics and Biochemistry, School of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15261, U.S.A.

The goal of experiments reported here was to identify the genes that encode capsid proteins VP21 and VP24 of herpes simplex virus type 1 (HSV-1). Capsids were isolated from infected cells and the proteins were separated by SDS-PAGE. N-terminal amino acid sequence analysis of partial CNBr digestion products, and of intact VP21, showed that it is encoded within the UL26 open reading frame (ORF) of HSV-1 beginning with codon 248 and probably extending to the end of the ORF (codon 635). Similar analysis of digestion products confirmed that VP24 is specified by codons 1 to 247 at the 5' end of the UL26 ORF. Each of the seven known capsid proteins has now been assigned to an ORF.

Received 6 May 1993; accepted 11 June 1993.


This article has been cited by other articles:


Home page
J. Virol.Home page
L. Scholtes and J. D. Baines
Effects of Major Capsid Proteins, Capsid Assembly, and DNA Cleavage/Packaging on the pUL17/pUL25 Complex of Herpes Simplex Virus 1
J. Virol., December 15, 2009; 83(24): 12725 - 12737.
[Abstract] [Full Text] [PDF]


Home page
J. Virol.Home page
K. Yang and J. D. Baines
Tryptophan Residues in the Portal Protein of Herpes Simplex Virus 1 Critical to the Interaction with Scaffold Proteins and Incorporation of the Portal into Capsids
J. Virol., November 15, 2009; 83(22): 11726 - 11733.
[Abstract] [Full Text] [PDF]


Home page
J. Virol.Home page
K. Yang and J. D. Baines
Proline and Tyrosine Residues in Scaffold Proteins of Herpes Simplex Virus 1 Critical to the Interaction with Portal Protein and Its Incorporation into Capsids
J. Virol., August 15, 2009; 83(16): 8076 - 8081.
[Abstract] [Full Text] [PDF]


Home page
J. Virol.Home page
A. P. de Oliveira, D. L. Glauser, A. S. Laimbacher, R. Strasser, E. M. Schraner, P. Wild, U. Ziegler, X. O. Breakefield, M. Ackermann, and C. Fraefel
Live Visualization of Herpes Simplex Virus Type 1 Compartment Dynamics
J. Virol., May 15, 2008; 82(10): 4974 - 4990.
[Abstract] [Full Text] [PDF]


Home page
J. Virol.Home page
A. K. Sheaffer, W. W. Newcomb, M. Gao, D. Yu, S. K. Weller, J. C. Brown, and D. J. Tenney
Herpes Simplex Virus DNA Cleavage and Packaging Proteins Associate with the Procapsid prior to Its Maturation
J. Virol., January 15, 2001; 75(2): 687 - 698.
[Abstract] [Full Text]


Home page
J. Virol.Home page
A. K. Sheaffer, W. W. Newcomb, J. C. Brown, M. Gao, S. K. Weller, and D. J. Tenney
Evidence for Controlled Incorporation of Herpes Simplex Virus Type 1 UL26 Protease into Capsids
J. Virol., August 1, 2000; 74(15): 6838 - 6848.
[Abstract] [Full Text]


Home page
J. Virol.Home page
J. H. I. Chi and D. W. Wilson
ATP-Dependent Localization of the Herpes Simplex Virus Capsid Protein VP26 to Sites of Procapsid Maturation
J. Virol., February 1, 2000; 74(3): 1468 - 1476.
[Abstract] [Full Text]


Home page
J. Virol.Home page
A. Dasgupta and D. W. Wilson
ATP Depletion Blocks Herpes Simplex Virus DNA Packaging and Capsid Maturation
J. Virol., March 1, 1999; 73(3): 2006 - 2015.
[Abstract] [Full Text]


Home page
J. Biol. Chem.Home page
D. R. O'Boyle II, K. Wager-Smith, J. T. Stevens III, and S. P. Weinheimer
The Effect of Internal Autocleavage on Kinetic Properties of the Human Cytomegalovirus Protease Catalytic Domain
J. Biol. Chem., March 3, 1995; 270(9): 4753 - 4758.
[Abstract] [Full Text] [PDF]




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
INT J SYST EVOL MICROBIOL MICROBIOLOGY J GEN VIROL
J MED MICROBIOL ALL SGM JOURNALS
Copyright © 1993 by the Society for General Microbiology.