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J Gen Virol 74 (1993), 917-920; DOI 10.1099/0022-1317-74-5-917
© 1993 Society for General Microbiology
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The Jeryl Lynn Vaccine Strain of Mumps Virus is a Mixture of Two Distinct Isolates

M. A. Afzal, A. R. Pickford, T. Forsey, A. B. Heath and P. D. Minor

National Institute for Biological Standards and Control, Blanche Lane, South Mimms, Potters Bar, Hertfordshire EN6 3QG, U.K.

Sequence analysis of the region of the mumps virus genome encoding the putative small hydrophobic protein gene confirms that it is a highly variable region. Jeryl Lynn, the mumps vaccine strain used in the U.K., is shown to be a mixture of two closely related viruses, both probably of American origin.

Received 21 October 1992; accepted 1 December 1992.


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