| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
1 Swedish Institute for Infectious Disease Control, S-105 21 Stockholm, Sweden
2 Department of Virology, Karolinska Institute, S-171 77 Stockholm, Sweden
3 Special Pathogens Branch, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
4 Anti-plague Station, Khabarovsk, Russia
5 Chumakov Institute of Poliomyelitis and Viral Encephalitides, Ac. Med. Sci., Moscow, Russia
and6 National Defence Research Establishment, FOA-4, S-901 82 Umeå, Sweden
Two hantavirus strains, MF43 and MF113, isolated from Microtus fortis trapped in the Khabarovsk region of far-eastern Russia, were analysed by direct nucleotide sequencing of PCR generated fragments of the M and S segments, by immunofluorescence and by focus reduction neturalization tests (FRNT). The nucleotide sequences revealed that the two isolates were closely related to each other but distinct from all other hantaviruses. Phylogenetic analysis of the M and S segments showed that the MF strains form a separate branch in the Hantavirus tree, positioned between the branches of Prospect Hill and Puumala viruses. The strains were shown to be serologically distinct from the other hantavirus serotypes by FRNT using immune rabbit sera. Puumala virus was the closest relative, both genetically and serologically. We propose that this new hantavirus serotype should be named Khabarovsk (KBR).
* Author for correspondence. Fax +46 8 7303248. e-mail Jan.Horling@smi.ki.se
Received 4 October 1995;
accepted 18 December 1995.
This article has been cited by other articles:
|
|
 |
|
  K.-J. Song, L. J. Baek, S. Moon, S. J. Ha, S. H. Kim, K. S. Park, T. A. Klein, W. Sames, H.-C. Kim, J. S. Lee, et al. Muju virus, a novel hantavirus harboured by the arvicolid rodent Myodes regulus in Korea J. Gen. Virol., November 1, 2007; 88(11): 3121 - 3129. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. L. Hughes and R. Friedman Evolutionary Diversification of Protein-Coding Genes of Hantaviruses Mol. Biol. Evol., October 1, 2000; 17(10): 1558 - 1568. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. McCAUGHEY and C.A. HART Hantaviruses J. Med. Microbiol., July 1, 2000; 49(7): 587 - 599. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 O. Vapalahti, A. Lundkvist, V. Fedorov, C. J. Conroy, S. Hirvonen, A. Plyusnina, K. Nemirov, K. Fredga, J. A. Cook, J. Niemimaa, et al. Isolation and Characterization of a Hantavirus from Lemmus sibiricus: Evidence for Host Switch during Hantavirus Evolution J. Virol., July 1, 1999; 73(7): 5586 - 5592. [Abstract] [Full Text]
|
|
|
|
 |
|
 I. Gavrilovskaya, R. LaMonica, M.-E. Fay, B. Hjelle, C. Schmaljohn, R. Shaw, and E. R. Mackow New York 1 and Sin Nombre Viruses Are Serotypically Distinct Viruses Associated with Hantavirus Pulmonary Syndrome J. Clin. Microbiol., January 1, 1999; 37(1): 122 - 126. [Abstract] [Full Text]
|
|
|
|
|
|
C. Sibold, H. Meisel, D. H. Kruger, M. Labuda, J. Lysy, O. Kozuch, M. Pejcoch, A. Vaheri, and A. Plyusnin Recombination in Tula Hantavirus Evolution: Analysis of Genetic Lineages from Slovakia J. Virol., January 1, 1999; 73(1): 667 - 675. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Morii, K. Yoshimatsu, J. Arikawa, G. Zhou, H. Kariwa, and I. Takashima Antigenic Characterization of Hantaan and Seoul Virus Nucleocapsid Proteins Expressed by Recombinant Baculovirus: Application of a Truncated Protein, Lacking an Antigenic Region Common to the Two Viruses, as a Serotyping Antigen J. Clin. Microbiol., September 1, 1998; 36(9): 2514 - 2521. [Abstract] [Full Text]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| INT J SYST EVOL MICROBIOL | MICROBIOLOGY | J GEN VIROL |
| J MED MICROBIOL | ALL SGM JOURNALS | |
