Journal of General Virology, Vol 79, 3027-3031, Copyright © 1998 by Society for General Microbiology

ARTICLES

Identification and characterization of the herpes simplex virus type 1 UL51 gene product

T Daikoku, K Ikenoya, H Yamada, F Goshima and Y Nishiyama
Laboratory of Virology, Research Institute for Disease Mechanism and Control, Nagoya University School of Medicine, Japan.

The products of the herpes simplex virus type 1 UL51 gene were identified as phosphoproteins with apparent molecular masses of 27, 29 and 30 kDa. The proteins were produced at the late stage of infection, in a manner highly dependent on viral DNA synthesis, and were associated with extracellular virions. Immunofluorescence studies localized the UL51 proteins mainly to the cytoplasm, both in infected Vero cells and in transfected COS-1 cells singly expressing the UL51 gene.

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