J Gen Virol Try IJSEM Online
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Reichert, M.
Right arrow Articles by Kettmann, R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Reichert, M.
Right arrow Articles by Kettmann, R.
Agricola
Right arrow Articles by Reichert, M.
Right arrow Articles by Kettmann, R.
Journal of General Virology (2000), 81, 965-969.
© 2000 Society for General Microbiology

Animal: RNA Viruses

Protective effects of a live attenuated bovine leukaemia virus vaccine with deletion in the R3 and G4 genes

M. Reichert1, G. H. Cantor2, L. Willems3 and R. Kettmann3

National Veterinary Research Institute, Pulawy, Poland1
Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA 99164-7040, USA2
Faculty of Agronomy, B-5030 Gembloux, Belgium3

Author for correspondence: Michal Reichert. Fax +48 81 8862595. e-mail reichert{at}piwet.pulawy.pl

In this study the protective effects of a live attenuated bovine leukaemia provirus (pBLVDX) with deletion in the R3 and G4 genes were tested. Six out of six sheep appeared to resist challenge with parental BLV344. Two out of three animals transfected with pBLVDX were protected against challenge with bovine leukaemia virus (BLV) from a naturally infected cow. As a model for the protection against infection by members of the human T-lymphotropic virus/BLV group, these data provide evidence that a DNA-based vaccination with an attenuated provirus is able to protect against challenge infections.




This article has been cited by other articles:


Home page
 J. Virol.Home page
A. Florins, N. Gillet, M. Boxus, P. Kerkhofs, R. Kettmann, and L. Willems
Even Attenuated Bovine Leukemia Virus Proviruses Can Be Pathogenic in Sheep
J. Virol., September 15, 2007; 81(18): 10195 - 10200.
[Abstract] [Full Text] [PDF]

Home page
 J. Virol.Home page
L. Lefebvre, V. Ciminale, A. Vanderplasschen, D. D'Agostino, A. Burny, L. Willems, and R. Kettmann
Subcellular Localization of the Bovine Leukemia Virus R3 and G4 Accessory Proteins
J. Virol., June 27, 2002; 76(15): 7843 - 7854.
[Abstract] [Full Text] [PDF]

Home page
 J. Gen. Virol.Home page
P. Kerkhofs, J.-S. Gatot, K. Knapen, M. Mammerickx, A. Burny, D. Portetelle, L. Willems, and R. Kettmann
Long-term protection against bovine leukaemia virus replication in cattle and sheep
J. Gen. Virol., April 1, 2000; 81(4): 957 - 963.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
INT J SYST EVOL MICROBIOL MICROBIOLOGY J GEN VIROL
J MED MICROBIOL ALL SGM JOURNALS
Copyright © 2000 by the Society for General Microbiology.