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Journal of General Virology (2001), 82, 227-232.
© 2001 Society for General Microbiology


Animal: DNA Viruses

Recognition of another member of the malignant catarrhal fever virus group: an endemic gammaherpesvirus in domestic goats

Hong Li1, Janice Keller1, Donald P. Knowles1,2 and Timothy B. Crawford2

Animal Diseases Research Unit, USDA-ARS1 and Department of Veterinary Microbiology and Pathology2, Washington State University, 3003 ADBF, Pullman, WA 99164-6630, USA

Author for correspondence: Hong Li. Fax +1 509 335 8328. e-mail hli{at}vetmed.wsu.edu

A novel gammaherpesvirus in goats that is herein tentatively designated as caprine herpesvirus-2 was identified based on the sequence of a fragment from the herpesvirus DNA polymerase gene. Sequence alignment analysis revealed that the virus sequence isolated from goats was 67% identical to the homologous sequence from alcelaphine herpesvirus-1, 71% identical to ovine herpesvirus-2 and 73% identical to a recently recognized herpesvirus causing malignant catarrhal fever in white-tailed deer. Combined serological and PCR-survey data demonstrated that this virus is endemic in goats and its transmission pattern may be similar to that of ovine herpesvirus-2 in sheep.




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