| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Insect |
Centre de recherche de microbiologie et biotechnologie, INRS-Institut Armand-Frappier, Université du Québec, 531 boul. des Prairies, Laval, QC, CanadaH7V 1B71
Department of Bioscience, Faculty of Agriculture, Hokkaido University, Sapporo, Japan2
Center of Virology-IRD, Faculty of Agriculture, University of Cairo, Giza, Cairo, Egypt3
Author for correspondence: Peter Tijssen. Fax +1 450 686 5626. e-mail peter.tijssen{at}inrs-iaf.uquebec.ca
Bombyx mori densovirus (BmDNV-1), on the basis of the previously reported genome sequence, constitutes by itself a separate genus (Iteravirus) within the Densovirinae subfamily of parvoviruses. Inconsistencies in the genome organization, however, necessitated its reassessment. The genome sequence of new clones was determined and resulted in a completely different genome organization. The corrected sequence also contained conserved sequence motifs found in other parvoviruses. Some amino acids in the highly conserved domain in the unique region of VP1 were shared by critical amino acids in the catalytic site and Ca2+-binding loop of secreted phospholipase A2, such as from snake and bee venoms. Expression of this domain and determination of enzyme activity demonstrated that capsids have a phospholipase A2 activity thus far unknown to occur in viruses. This viral phospholipase A2, which is required shortly after entry into the cell, showed a substrate preference for phosphatidylethanolamine and phosphatidylcholine over phosphatidylinositol.
This article has been cited by other articles:
|
|
 |
|
  E. Baquerizo-Audiot, A. Abd-Alla, F.-X. Jousset, F. Cousserans, P. Tijssen, and M. Bergoin Structure and Expression Strategy of the Genome of Culex pipiens Densovirus, a Mosquito Densovirus with an Ambisense Organization J. Virol., July 1, 2009; 83(13): 6863 - 6873. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Vendeville, M. Ravallec, F.-X. Jousset, M. Devise, D. Mutuel, M. Lopez-Ferber, P. Fournier, T. Dupressoir, and M. Ogliastro Densovirus Infectious Pathway Requires Clathrin-Mediated Endocytosis Followed by Trafficking to the Nucleus J. Virol., May 1, 2009; 83(9): 4678 - 4689. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Ros, M. Gerber, and C. Kempf Conformational Changes in the VP1-Unique Region of Native Human Parvovirus B19 Lead to Exposure of Internal Sequences That Play a Role in Virus Neutralization and Infectivity J. Virol., December 15, 2006; 80(24): 12017 - 12024. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Lupescu, C.-T. Bock, P. A. Lang, S. Aberle, H. Kaiser, R. Kandolf, and F. Lang Phospholipase A2 Activity-Dependent Stimulation of Ca2+ Entry by Human Parvovirus B19 Capsid Protein VP1 J. Virol., November 15, 2006; 80(22): 11370 - 11380. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Wang, J. Zhang, H. Jiang, C. Liu, F. Yi, and Y. Hu Nucleotide sequence and genomic organization of a newly isolated densovirus infecting Dendrolimus punctatus J. Gen. Virol., August 1, 2005; 86(8): 2169 - 2173. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Kronenberg, B. Bottcher, C. W. von der Lieth, S. Bleker, and J. A. Kleinschmidt A Conformational Change in the Adeno-Associated Virus Type 2 Capsid Leads to the Exposure of Hidden VP1 N Termini J. Virol., May 1, 2005; 79(9): 5296 - 5303. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Bleker, F. Sonntag, and J. A. Kleinschmidt Mutational Analysis of Narrow Pores at the Fivefold Symmetry Axes of Adeno-Associated Virus Type 2 Capsids Reveals a Dual Role in Genome Packaging and Activation of Phospholipase A2 Activity J. Virol., February 15, 2005; 79(4): 2528 - 2540. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. L. Farkas, Z. Zadori, M. Benko, S. Essbauer, B. Harrach, and P. Tijssen A parvovirus isolated from royal python (Python regius) is a member of the genus Dependovirus J. Gen. Virol., March 1, 2004; 85(3): 555 - 561. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Abd-Alla, F.-X. Jousset, Y. Li, G. Fediere, F. Cousserans, and M. Bergoin NS-3 Protein of the Junonia coenia Densovirus Is Essential for Viral DNA Replication in an Ld 652 Cell Line and Spodoptera littoralis Larvae J. Virol., January 15, 2004; 78(2): 790 - 797. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Tijssen, Y. Li, M. El-Far, J. Szelei, M. Letarte, and Z. Zadori Organization and Expression Strategy of the Ambisense Genome of Densonucleosis Virus of Galleria mellonella J. Virol., October 1, 2003; 77(19): 10357 - 10365. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. van Munster, A. M. Dullemans, M. Verbeek, J. F. J. M. van den Heuvel, C. Reinbold, V. Brault, A. Clerivet, and F. van der Wilk A new virus infecting Myzus persicae has a genome organization similar to the species of the genus Densovirus J. Gen. Virol., January 1, 2003; 84(1): 165 - 172. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Ros, C. J. Burckhardt, and C. Kempf Cytoplasmic Trafficking of Minute Virus of Mice: Low-pH Requirement, Routing to Late Endosomes, and Proteasome Interaction J. Virol., November 13, 2002; 76(24): 12634 - 12645. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Dorsch, G. Liebisch, B. Kaufmann, P. von Landenberg, J. H. Hoffmann, W. Drobnik, and S. Modrow The VP1 Unique Region of Parvovirus B19 and Its Constituent Phospholipase A2-Like Activity J. Virol., February 15, 2002; 76(4): 2014 - 2018. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| INT J SYST EVOL MICROBIOL | MICROBIOLOGY | J GEN VIROL |
| J MED MICROBIOL | ALL SGM JOURNALS | |
