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Ovine herpesvirus 2 lytic cycle replication and capsid production

Laboratory for Clinical and Molecular Virology, The University of Edinburgh, Summerhall, Edinburgh, UK¹
Moredun Research Institute, Pentlands Science Park, Penicuik, UK²

Author for correspondence: James Stewart. Present address: Centre for Comparative Infectious Diseases, The University of Liverpool, Dept of Medical Microbiology and Genitourinary Medicine, Duncan Building, Daulby Street, Liverpool L69 3GA, UK. Fax +44 151 706 5805. e-mail j.p.stewart{at}liv.ac.uk

Ovine herpesvirus 2 (OvHV-2) causes malignant catarrhal fever in cattle, pigs and deer. We have observed intact circular and linear OvHV-2 genomes in infected T cell lines derived from cows and rabbits. Bovine T cell lines were predominantly latently infected but rabbit T cell lines supported OvHV-2 productive cycle gene expression and virus capsids were demonstrated for the first time.

This article has been cited by other articles:

				J. Hart, M. Ackermann, G. Jayawardane, G. Russell, D. M. Haig, H. Reid, and J. P. Stewart Complete sequence and analysis of the ovine herpesvirus 2 genome J. Gen. Virol., January 1, 2007; 88(1): 28 - 39. [Abstract] [Full Text] [PDF]