| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Review article |
A. N. Belozersky Institute of Physico-Chemical Biology, Moscow State University, Moscow 119899, Russia
Correspondence
Sergey Yu. Morozov
morozov{at}genebee.msu.su
Many plant virus genera encode a ‘triple gene block’ (TGB), a specialized evolutionarily conserved gene module involved in the cell-to-cell and long-distance movement of viruses. The TGB-based transport system exploits the co-ordinated action of three polypeptides to deliver viral genomes to plasmodesmata and to accomplish virus entry into neighbouring cells. Although data obtained on both the TGB and well-studied single protein transport systems clearly demonstrate that plant viruses employ host cell pathways for intra- and intercellular trafficking of genomic nucleic acids and proteins, there is no integral picture of the details of molecular events during TGB-mediated virus movement. Undoubtedly, understanding the molecular basis of the concerted action of TGB-encoded proteins in transporting viral genomes from cell to cell should provide new insights into the general principles of movement protein function. This review describes the structure, phylogeny and expression of TGB proteins, their roles in virus cell-to-cell movement and potential influence on host antiviral defences.
Published ahead of print on 18 March 2003 as DOI 10.1099/vir.0.18922-0
This article has been cited by other articles:
|
|
 |
|
  V. V. Makarov, E. N. Rybakova, A. V. Efimov, E. N. Dobrov, M. V. Serebryakova, A. G. Solovyev, I. V. Yaminsky, M. E. Taliansky, S. Yu. Morozov, and N. O. Kalinina Domain organization of the N-terminal portion of hordeivirus movement protein TGBp1 J. Gen. Virol., December 1, 2009; 90(12): 3022 - 3032. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. Gomez, R. N. Sempere, S. F. Elena, and M. A. Aranda Mixed Infections of Pepino Mosaic Virus Strains Modulate the Evolutionary Dynamics of this Emergent Virus J. Virol., December 1, 2009; 83(23): 12378 - 12387. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H.-S. Lim, J. N. Bragg, U. Ganesan, S. Ruzin, D. Schichnes, M. Y. Lee, A. M. Vaira, K. H. Ryu, J. Hammond, and A. O. Jackson Subcellular Localization of the Barley Stripe Mosaic Virus Triple Gene Block Proteins J. Virol., September 15, 2009; 83(18): 9432 - 9448. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Martinez-Gil, J. A. Sanchez-Navarro, A. Cruz, V. Pallas, J. Perez-Gil, and I. Mingarro Plant Virus Cell-to-Cell Movement Is Not Dependent on the Transmembrane Disposition of Its Movement Protein J. Virol., June 1, 2009; 83(11): 5535 - 5543. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Senshu, J. Ozeki, K. Komatsu, M. Hashimoto, K. Hatada, M. Aoyama, S. Kagiwada, Y. Yamaji, and S. Namba Variability in the level of RNA silencing suppression caused by triple gene block protein 1 (TGBp1) from various potexviruses during infection J. Gen. Virol., April 1, 2009; 90(4): 1014 - 1024. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H.-S. Lim, J. N. Bragg, U. Ganesan, D. M. Lawrence, J. Yu, M. Isogai, J. Hammond, and A. O. Jackson Triple Gene Block Protein Interactions Involved in Movement of Barley Stripe Mosaic Virus J. Virol., May 15, 2008; 82(10): 4991 - 5006. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. V. Schepetilnikov, A. G. Solovyev, E. N. Gorshkova, J. Schiemann, A. I. Prokhnevsky, V. V. Dolja, and S. Y. Morozov Intracellular Targeting of a Hordeiviral Membrane-Spanning Movement Protein: Sequence Requirements and Involvement of an Unconventional Mechanism J. Virol., February 1, 2008; 82(3): 1284 - 1293. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Verchot-Lubicz, C.-M. Ye, and D. Bamunusinghe Molecular biology of potexviruses: recent advances J. Gen. Virol., June 1, 2007; 88(6): 1643 - 1655. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
X. Yuan, Y. Cao, D. Xi, L. Guo, C. Han, D. Li, Y. Zhai, and J. Yu Analysis of the subgenomic RNAs and the small open reading frames of Beet black scorch virus. J. Gen. Virol., October 1, 2006; 87(Pt 10): 3077 - 3086. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. D. Leshchiner, A. G. Solovyev, S. Yu. Morozov, and N. O. Kalinina A minimal region in the NTPase/helicase domain of the TGBp1 plant virus movement protein is responsible for ATPase activity and cooperative RNA binding. J. Gen. Virol., October 1, 2006; 87(Pt 10): 3087 - 3095. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
O. V. Karpova, O. V. Zayakina, M. V. Arkhipenko, E. V. Sheval, O. I. Kiselyova, V. Yu. Poljakov, I. V. Yaminsky, N. P. Rodionova, and J. G. Atabekov Potato virus X RNA-mediated assembly of single-tailed ternary 'coat protein-RNA-movement protein' complexes J. Gen. Virol., September 1, 2006; 87(9): 2731 - 2740. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Torrance, G. H. Cowan, T. Gillespie, A. Ziegler, and C. Lacomme Barley stripe mosaic virus-encoded proteins triple-gene block 2 and {gamma}b localize to chloroplasts in virus-infected monocot and dicot plants, revealing hitherto-unknown roles in virus replication. J. Gen. Virol., August 1, 2006; 87(Pt 8): 2403 - 2411. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M.-K. Lin, C.-C. Hu, N.-S. Lin, B.-Y. Chang, and Y.-H. Hsu Movement of potexviruses requires species-specific interactions among the cognate triple gene block proteins, as revealed by a trans-complementation assay based on the bamboo mosaic virus satellite RNA-mediated expression system. J. Gen. Virol., May 1, 2006; 87(Pt 5): 1357 - 1367. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. I. Prokhnevsky, V. V. Peremyslov, and V. V. Dolja Actin Cytoskeleton Is Involved in Targeting of a Viral Hsp70 Homolog to the Cell Periphery J. Virol., November 15, 2005; 79(22): 14421 - 14428. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. I. Lukhovitskaya, N. E. Yelina, A. A. Zamyatnin Jr, M. V. Schepetilnikov, A. G. Solovyev, M. Sandgren, S. Yu. Morozov, J. P. T. Valkonen, and E. I. Savenkov Expression, localization and effects on virulence of the cysteine-rich 8 kDa protein of Potato mop-top virus J. Gen. Virol., October 1, 2005; 86(10): 2879 - 2889. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. V. Schepetilnikov, U. Manske, A. G. Solovyev, A. A. Zamyatnin Jr, J. Schiemann, and S. Yu. Morozov The hydrophobic segment of Potato virus X TGBp3 is a major determinant of the protein intracellular trafficking J. Gen. Virol., August 1, 2005; 86(8): 2379 - 2391. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. S. Nelson and V. Citovsky Plant Viruses. Invaders of Cells and Pirates of Cellular Pathways Plant Physiology, August 1, 2005; 138(4): 1809 - 1814. [Full Text] [PDF]
|
|
|
|
|
|
H.-J. Ju, T. D. Samuels, Y.-S. Wang, E. Blancaflor, M. Payton, R. Mitra, K. Krishnamurthy, R. S. Nelson, and J. Verchot-Lubicz The Potato Virus X TGBp2 Movement Protein Associates with Endoplasmic Reticulum-Derived Vesicles during Virus Infection Plant Physiology, August 1, 2005; 138(4): 1877 - 1895. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Ajjikuttira, C.-S. Loh, and S.-M. Wong Reciprocal function of movement proteins and complementation of long-distance movement of Cymbidium mosaic virus RNA by Odontoglossum ringspot virus coat protein J. Gen. Virol., May 1, 2005; 86(5): 1543 - 1553. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Haupt, G. H. Cowan, A. Ziegler, A. G. Roberts, K. J. Oparka, and L. Torrance Two Plant-Viral Movement Proteins Traffic in the Endocytic Recycling Pathway PLANT CELL, January 1, 2005; 17(1): 164 - 181. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. V. Peremyslov, Y.-W. Pan, and V. V. Dolja Movement Protein of a Closterovirus Is a Type III Integral Transmembrane Protein Localized to the Endoplasmic Reticulum J. Virol., April 1, 2004; 78(7): 3704 - 3709. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| INT J SYST EVOL MICROBIOL | MICROBIOLOGY | J GEN VIROL |
| J MED MICROBIOL | ALL SGM JOURNALS | |
