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J Gen Virol 85 (2004), 21-24; DOI 10.1099/vir.0.19427-0

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© 2004 Society for General Microbiology

Short Communication

A novel simian immunodeficiency virus isolated from a Schmidt's guenon (Cercopithecus ascanius schmidti)

Ernst J. Verschoor, Zahra Fagrouch, Ilja Bontjer, Henk Niphuis and Jonathan L. Heeney

Department of Virology, Biomedical Primate Research Centre (BPRC), PO Box 3306, 2206 GH Rijswijk, The Netherlands

Correspondence
Ernst Verschoor
verschoor{at}bprc.nl

A novel simian immunodeficiency virus (SIV) was characterized from a Schmidt's guenon (Cercopithecus ascanius schmidti), which was housed in a local zoo. The virus infection was detected during a routine serological screening for antibodies that were cross-reactive with SIVmac antigens. Infection with an immunodeficiency virus was confirmed using an INNO-LIA HIV Confirmation assay. Using DNA isolated from a blot clot, a 1895 nt partial pol sequence was amplified and sequenced. Phylogenetic analysis showed that this virus, designated SIVschm, shares a distant relationship with SIVgsn, isolated from greater spot-nosed monkeys, and is one of the most divergent SIVs identified to date.

Published ahead of print on 30 September 2003 as DOI 10.1099/vir.0.19427-0.




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