|
|
||||||||
Short Communication |
Laboratoire de Virologie et Barrière d'Espèces, UR086, INRA, Centre de Recherche de Tours, 37380 Nouzilly, France
Correspondence
D. Rasschaert
rasschae{at}tours.inra.fr
The genes UL18, UL19, UL26, UL26.5, UL35 and UL38 of Marek's disease virus 1 (MDV-1) strain RB1B, encoding the homologues of herpes simplex virus type 1 (HSV-1) capsid proteins VP23, VP5, VP21VP24, preVP22a, VP26 and VP19C, were identified and sequenced. Recombinant baculoviruses were used to express the six capsid genes in insect cells. Coexpression of the six genes or of UL18, UL19, UL26.5 and UL38 in insect cells resulted in the formation of capsids with a large core. In addition, electron microscopy of thin sections clearly revealed the presence of large numbers of small spherical particles. Experimental coinfection demonstrated that these small particles were associated with production of the preVP22a protein.
This article has been cited by other articles:
![]() |
S. Laurent, C. Blondeau, M. Belghazi, S. Remy, E. Esnault, P. Rasschaert, and D. Rasschaert Sequential Autoprocessing of Marek's Disease Herpesvirus Protease Differs from That of Other Herpesviruses J. Virol., June 1, 2007; 81(11): 6117 - 6121. [Abstract] [Full Text] [PDF] |
||||
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| INT J SYST EVOL MICROBIOL | MICROBIOLOGY | J GEN VIROL |
| J MED MICROBIOL | ALL SGM JOURNALS | |