HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Bourhy, H. Articles by Walker, P. J. Search for Related Content PubMed PubMed Citation Articles by Bourhy, H. Articles by Walker, P. J. Agricola Articles by Bourhy, H. Articles by Walker, P. J.

Phylogenetic relationships among rhabdoviruses inferred using the L polymerase gene

¹ Rabies Laboratory, WHO Collaborating Centre for Reference and Research on Rabies, Institut Pasteur, 28 rue du docteur Roux, 75724 Paris Cedex 15, France
² CSIRO Livestock Industries, Queensland Bioscience Precinct, 306 Carmody Road, St Lucia, QLD 4067, Australia
³ Department of Biology, The Pennsylvania State University, Mueller Laboratory, University Park, PA 16802, USA
⁴ CSIRO Livestock Industries, Australian Animal Health Laboratory, 5 Portarlington Road, Geelong, VIC 3220, Australia

Correspondence
H. Bourhy
hbourhy{at}pasteur.fr

RNA viruses of the family Rhabdoviridae include arthropod-borne agents that infect plants, fish and mammals, and also include a variety of non-vector-borne mammalian viruses. Herein is presented a molecular phylogenetic analysis, the largest undertaken to date, of 56 rhabdoviruses, including 20 viruses which are currently unassigned or assigned as tentative species within the Rhabdoviridae. Degenerate primers targeting a region of block III of the L polymerase gene were defined and used for RT-PCR amplification and sequencing. A maximum-likelihood phylogenetic analysis of a 158-residue L polymerase amino acid sequence produced an evolutionary tree containing the six recognized genera of the Rhabdoviridae and also enabled us to identify four more monophyletic groups of currently unclassified rhabdoviruses that we refer to as the ‘Hart Park’, ‘Almpiwar’, ‘Le Dantec’ and ‘Tibrogargan’ groups. The broad phylogenetic relationships among these groups and genera also indicate that the evolutionary history of rhabdoviruses was strongly influenced by mode of transmission, host species (plant, fish or mammal) and vector (orthopteran, homopteran or dipteran).

This article has been cited by other articles:

				C. Talbi, E. C. Holmes, P. de Benedictis, O. Faye, E. Nakoune, D. Gamatie, A. Diarra, B. O. Elmamy, A. Sow, E. V. Adjogoua, et al. Evolutionary history and dynamics of dog rabies virus in western and central Africa J. Gen. Virol., April 1, 2009; 90(4): 783 - 791. [Abstract] [Full Text] [PDF]

				I. V. Kuzmin, G. J. Hughes, and C. E. Rupprecht Phylogenetic relationships of seven previously unclassified viruses within the family Rhabdoviridae using partial nucleoprotein gene sequences. J. Gen. Virol., August 1, 2006; 87(Pt 8): 2323 - 2331. [Abstract] [Full Text] [PDF]