HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Ogawa, T. Articles by Shirasawa, H. Search for Related Content PubMed PubMed Citation Articles by Ogawa, T. Articles by Shirasawa, H. Agricola Articles by Ogawa, T. Articles by Shirasawa, H.

Complete genome and phylogenetic position of bovine papillomavirus type 7

¹ Division of Virology, Chiba Prefectural Institute of Public Health, 666-2 Nitona-cho, Chuou-ku, Chiba 260-8715, Japan
² Department of Molecular Virology, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuou-ku, Chiba 260-8670, Japan

Correspondence
Yoshimi Tomita
tomita{at}faculty.chiba-u.jp

Six bovine papillomavirus (BPV) types and 16 putative BPV types have been reported previously. Here, the complete genome sequence of BAPV6, a novel putative BPV type isolated from cattle in Japan, was determined by using multiple-primed rolling-circle amplification. The genome consisted of 7412 bp (G+C content of 46 mol%) that encoded five early (E1, E2, E4, E6 and E7) and two late (L1 and L2) genes, but did not encode the E5 gene. The E6 protein contained a non-consensus CxxC(x)₃₃CxxC and a consensus CxxC(x)₂₉CxxC zinc-binding domain, and the E7 protein lacked the LxCxE motif. The nucleotide sequence of the L1 open reading frame (ORF) was related most closely (57–58 %) to the L1 ORF of member(s) of the genera Betapapillomavirus, Gammapapillomavirus and Pipapillomavirus. Phylogenetic analysis based on the complete L1 ORF suggests that BAPV6 should be classified in a novel genus in the family Papillomaviridae as BPV-7.

The GenBank/EMBL/DDBJ accession number for the complete genome sequence of BPV-7 is DQ217793.

This article has been cited by other articles:

				S. Hatama, K. Nobumoto, and T. Kanno Genomic and phylogenetic analysis of two novel bovine papillomaviruses, BPV-9 and BPV-10 J. Gen. Virol., January 1, 2008; 89(1): 158 - 163. [Abstract] [Full Text] [PDF]