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Prion clearance in bigenic mice, by J. G. Safar, S. J. DeArmond, K. Kociuba, C. Deering, S. Didorenko, E. Bouzamondo-Bernstein, S. B. Prusiner and P. Tremblay

Journal of General Virology vol. 86, part 10, pp. 2913 - 2923

Supplementary Fig. S1. Accumulation of PrPSc and rPrPSc in the brains of RML-infected bigenic mice

Supplementary Fig. S2. Clearance of PrPSc and rPrPSc from the brains of RML-infected Tg(tTA:PrP+/0)3 mice

Supplementary Fig. S3. Neuropathological profiles of RML-inoculated Tg(tTA:PrP+/0)3 mice showing the impact of PrPC depletion on PrPSc deposits in the cerebellum

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