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Fig. 5. Effect of different time points of SIP oral administration in the protection of piglets against TGEV infection. The first SIP dose was provided orally to the piglets 6 h before (A), at the same time as (B) or 6 h after (C) virus challenge. Virus titres in lung and gut tissues [p.f.u. (g tissue)1] after oral administration of neutralizing sw- SIP-6A.C3 or negative-control sw- SIP-irr. SIP-containing supernatants are shown. Mean+SD titres from three animals are represented. No Ab, infected piglets to which no antibody was administered.
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