Investigation of a role for lysine residues in non-structural proteins 2 and 2/3 of the hepatitis C virus for their degradation and virus assembly, by Sarah Welbourn, Vlastimil Jirasko, Valérie Breton, Simon Reiss, Francois Penin, Ralf Bartenschlager and Arnim Pause
Journal of General Virology vol. 90, part 5, pp. 1071–1080
Supplementary Material. Supplementary methods, results and references. [PDF] (151 KB)
Supplementary Fig. S1. Effect of genotype on NS2 half-life.
Supplementary Fig. S2. Effect of K1028R on infectivity at early time points.
Supplementary Fig. S3. Effect of K1028R on NS2/3 cleavage.
Supplementary Fig. S4. Polyprotein processing in presence of mutant NS2/3.
[Single PDF] (1 MB)