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Front cover illustration

HeLa cells infected with encephalomyocarditis virus (EMCV) and harvested at 2 (top left), 4 (top right) and 6 h (bottom) post-infection. Cells were fixed, permeabilized and stained with anti-3D antibodies (visualizing EMCV 3D polymerase). Then the cells were incubated with anti-mouse FITC-conjugated antibodies (green) and TxR-conjugated wheat germ agglutinin (red), localizing Golgi and nuclear membranes. Image courtesy Aleksey Aminev, Institute for Molecular Virology, University of Wisconsin-Madison, Madison, WI, USA. See the paper by Amineva et al. in this issue, pp. 2969-2979.