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Front cover illustration

Silencing the expression of the rotavirus non-structural NSP5 protein (red) by RNA interference causes a redistribution of the viral structural protein VP6 (green) from its usual localization in viroplasms (yellow in the right cell, due to the co-localization of NSP5 and VP6) to fibres along the cell cytoplasm (left cell). The VP6 fibres do not co-localize with actin filaments (in magenta). Nuclei are stained in blue. Image courtesy Tomás López, Instituto de Biotecnología/UNAM, México. See the paper by López et al. in this issue, pp. 1609-1617.