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Front cover illustration

Immunohistochemical detection of gliosis at the level of midbrain (top), cerebellum (middle) and thalamus (bottom) in BoPrP^5OR-Tg mice after intracerebral BSE inoculation. Image courtesy Juan M. Torres, Centro de Investigación en Sanidad Animal, Madrid, Spain. See the paper by Brun et al. in the June issue of the journal, pp. 1842-1849.