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Front cover illustration

A poorly endotheliotropic and a highly endotheliotropic strain of human cytomegalovirus were compared with regard to their nuclear localization efficiency of incoming virus particles in HUVEC at 6 h after infection. Viral structural antigen pUL32 was visualized by indirect green immunofluorescence (punctate signals). Cellular tubulin was visualized by indirect red immunofluorescence (tubular signals). Counterstaining was done with DAPI (blue nuclear signals). Nuclei are 15 μm in diameter. Image courtesy Dr Christian Sinzger, Institute of Medical Virology, University of Tübingen, Germany. See the paper by Sinzger et al. in this issue, pp. 359–368.



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