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Front cover illustration

Immunofluorescence localization of RGV 53R. FHM cells were infected with RGV for 24 h and the cells were fixed, permeabilized and stained with anti-RGV 53R serum and FITC-conjugated anti-mouse antibody, followed by DAPI. Magnification ×100 (oil-immersion objective). Image courtesy Dr Qi-Ya Zhang, State Key Laboratory of Freshwater Ecology and Biotechnology, Chinese Academy of Sciences, Wuhan, People's Republic of China. See the paper by Zhao et al. in this issue, pp. 1866–1872.