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Front cover illustration

Nucleolar antigen upstream binding factor (UBF) and herpes simplex virus (HSV-1) infection. Confocal microscopy showing the location of three different UBF–EGFP fusion proteins together with HSV-1 replication compartments as marked by ICP-8 antisera. Image courtesy of Dr David A. Matthews, University of Bristol, UK. See the paper by Stow et al. in this issue, pp. 69–73.